For example:
* Correct: I need to go to the store.
* Incorrect: I, need to go to the store.
Here's when you might use a comma with "need":
* In a list: I need milk, eggs, and bread.
* After an introductory phrase: Because I need to go to the store, I'll leave soon.
* To separate clauses in a complex sentence: I need to go to the store, but I'm running late.
Let me know if you'd like more examples or have a specific sentence in mind!