Here are some options depending on the context:
* If it's a person's name: You would simply use "Wayne" as the name.
* If it's a slang expression like "Whatever, Wayne": You could use something like "Lo que sea" or "No me importa" (It doesn't matter).
* If it's part of a phrase like "Way out": You would need to translate the whole phrase, such as "Muy lejos" (very far) or "Fuera de lugar" (out of place).
In short, you need to provide more context for a proper translation. Let me know if you can give me more information about how "Wayne" is used, and I can give you a more accurate translation.