Formal:
* Non. (This is the most common and neutral way to say no.)
* Pas du tout. (This means "not at all" and emphasizes the negative.)
Informal:
* Non. (This is also the most common and neutral way to say no in informal situations.)
* Nan. (This is a more casual and familiar way to say no.)
* Nope. (This is an informal way to say no borrowed from English.)
Other options:
* Je ne sais pas. (This means "I don't know" and can be used as a way to decline a request.)
* Je ne peux pas. (This means "I can't" and is used to politely decline something you are unable to do.)
* Je préfère ne pas. (This means "I prefer not to" and is a more polite way to decline something.)
The best way to say no depends on the situation and your relationship with the person you are speaking to.