General meaning: "in", "into", "on", "upon"
* encage: to put in a cage
* enchant: to cast a spell on
* enclose: to surround or confine
* encode: to convert into a code
* encounter: to meet unexpectedly
* endure: to bear or tolerate
* engage: to become involved
* engrave: to carve into a surface
* enlighten: to inform or teach
* enlist: to join the military or other organization
* enquire: to ask for information
* enrich: to make richer or more valuable
* enrol: to register or sign up for something
* enslave: to make someone a slave
* ensure: to make certain
* enter: to go into
* enthrone: to place on a throne
* entitle: to give the right to
* entrap: to catch in a trap
* entrust: to give something to someone to care for
* envelop: to surround or enclose
* enumerate: to list or count
* envision: to imagine or picture in the mind
* environment: the surroundings or conditions
Meaning: "make", "cause to be"
* enable: to make possible
* enact: to make into law
* encourage: to give hope or confidence
* endanger: to put in danger
* enfeeble: to weaken
* enfranchise: to give the right to vote
* engender: to cause or produce
* enhance: to improve or make better
* enlarge: to make bigger
* enliven: to make more lively
* enrich: to make richer or more valuable
* enrobe: to dress in a robe
* ensnare: to trap or entangle
* ensure: to make certain
* entail: to involve or necessitate
* entertain: to amuse or interest
* entice: to tempt or persuade
* entwine: to twist or wrap around
* envision: to imagine or picture in the mind
This is just a small selection - there are many more words beginning with "en-." Keep in mind that some words that begin with "en-" might not be considered a true prefix, like "enough."