Nouns:
* -y: needy (someone in need)
* -er: need-er (a person who needs something)
* -ing: needing (the state of needing something)
Adjectives:
* -ful: needful (necessary, required)
* -less: needless (unnecessary, not required)
Verbs:
* -ed: needed (past tense of need)
* -ing: needing (present participle of need)
Other:
* -s: needs (plural form of need)
The specific suffix you choose will depend on the meaning you want to convey.