Here are some ways to use "que lo tuyo":
* "Vas a un examen? Que lo tuyo!" (You're going to an exam? Keep it up!)
* "Buena suerte con el proyecto. Que lo tuyo!" (Good luck with the project. Keep it up!)
* "Estoy seguro de que vas a ganar. Que lo tuyo!" (I'm sure you're going to win. Good luck!)
It can also be used in a more sarcastic way, implying that the person is unlikely to succeed:
* "Vas a intentar escalar el Everest? Que lo tuyo..." (You're going to try climbing Everest? Good luck with that...)
In general, "que lo tuyo" is a friendly and encouraging expression that can be used in a variety of situations.