Emphasis on Contrast:
* While the weather was beautiful, we decided to stay indoors.
* While most people prefer coffee, I'm a tea drinker.
Concession:
* While I understand your concerns, I still believe this is the right decision.
* While I'm not a fan of spicy food, I'll try this dish.
Simultaneous Actions:
* While the children played, their parents chatted.
* While she cooked, he cleaned the kitchen.
Duration:
* While I was waiting for the bus, I saw a funny dog.
* While we were on vacation, we visited several museums.
Other uses:
* While it's true that you're right, I still think we should try something different.
* While you're at it, could you also pick up some milk?
Remember that "while" often introduces a clause that contrasts with or adds information to the main clause.