Simple:
* Years of hard work culminated in her successful graduation from medical school.
* The long, arduous journey culminated in a breathtaking view from the mountaintop.
With specific details:
* The team's tireless research and development culminated in the creation of a revolutionary new drug.
* The protests, which began as small gatherings, culminated in a massive demonstration demanding political change.
Figurative language:
* Her feelings of doubt and anxiety culminated in a crippling panic attack.
* The escalating tension between the two countries culminated in an all-out war.
Remember:
* "Culminated in" implies a process or series of events that lead to a final result or outcome.
* It often suggests a sense of achievement or completion.