Formal:
* On duty
* In the office
* Performing job responsibilities
* Engaged in professional activities
* Working (This is a bit more general)
Informal:
* On the job
* At the grind
* Clocking in
* Putting in hours
* Busting my hump (more slangy)
More specific:
* On site (if referring to a physical location)
* Remotely (if working from home)
* In the field (if referring to a specific profession)
The best alternative depends on the specific situation and the desired tone.