Here's a breakdown of its significance:
* Reduced form of NADP+: NADPH is the reduced form of NADP+, its oxidized counterpart. This means it carries high-energy electrons.
* Electron carrier: NADPH acts as an electron carrier, transferring electrons from one molecule to another.
* Biosynthesis: It plays a critical role in biosynthesis, specifically in the production of fatty acids, cholesterol, and steroids.
* Reducing power: NADPH provides reducing power, which is necessary for many metabolic reactions, including the detoxification of harmful molecules and the protection of cells against oxidative damage.
* Photosynthesis: In photosynthesis, NADPH is generated during the light-dependent reactions and used in the Calvin cycle to convert carbon dioxide into sugars.
In summary: NADPH is an essential coenzyme involved in a variety of metabolic processes, particularly those requiring reducing power and electron transfer. It plays a critical role in biosynthesis, detoxification, and the protection of cells from oxidative stress.