For medical procedures:
* Surgery
* Procedure
* Treatment
* Intervention
* Process
For business and military contexts:
* Action
* Task
* Mission
* Project
* Undertaking
For general use:
* Activity
* Function
* Process
* Action
* Work
For specific types of operations:
* Campaign (marketing, political)
* Deployment (military)
* Execution (plan)
* Implementation (plan)
To give you the most accurate replacement, please provide more context about what kind of operation you're referring to.