* Large in size or scope: Like "macromolecule" (a large molecule) or "macroeconomics" (the study of the overall economy).
* Relating to a large scale: As in "macro photography" (photography that captures a broad view) or "macroclimate" (the climate of a large region).
* Long in duration: Such as "macroevolution" (evolutionary change over long periods) or "macrohistory" (the study of long-term historical trends).
Essentially, "macro" signifies bigness or largeness in some context.