For "a person who is unreliable or irresponsible":
* Airhead
* Deadbeat
* Ditz
* Flibbertigibbet
* Flip-flopper
* Free spirit (depending on the tone)
* Lightweight
* Loafer
* Slob
* Space cadet
* Wishy-washy
For "a small piece of something, especially something that has broken off":
* Chip
* Fragment
* Piece
* Shard
* Splinter
* Strip
For "a thin, flat piece of something, especially snow":
* Crystal
* Powder
* Scale
* Sheet
For "to peel off in flakes":
* Exfoliate
* Peel
* Shred
* Shedding
For "to fail to keep a promise or commitment":
* Back out
* Bail
* Blow off
* Cancel
* Chicken out
* Go back on your word
* Stand someone up
* Wimp out
Please provide more context about how you're using "flake" so I can give you the most accurate synonyms!