If "brief" means "short in duration":
* Long
* Extended
* Prolonged
* Extensive
If "brief" means "short in length":
* Long
* Detailed
* Comprehensive
* Extensive
If "brief" means "concise":
* Verbose
* Wordy
* Rambling
* Prolix
If "brief" means "summary":
* Detailed
* Comprehensive
* Full
* Extensive
So, the best opposite for "brief" will depend on the specific situation.