Simple: The profligate gambler lost all his money in a single night.
Formal: The government's profligate spending habits have led to a national debt crisis.
Figurative: Despite her profligate use of language, she never truly conveyed her deepest feelings.
With contrast: While her brother was known for his profligate ways, she was always careful and frugal.
Descriptive: The profligate artist lived a life of luxury, surrounded by beautiful objects but with little concern for financial security.