* He played a bluesy tune on his mouthorgan, his face contorted with concentration. (This uses the word in a simple, descriptive way.)
* The street musician's mouthorgan filled the air with a joyful melody. (This sentence focuses on the sound of the instrument.)
* After years of neglect, the old mouthorgan was finally brought back to life with a good cleaning and a new reed set. (This sentence uses the word in a more specific context.)
* Learning to play the mouthorgan requires patience and practice, but the rewards are immense. (This sentence uses the word in a broader, more general context.)
Let me know if you'd like more examples, or if you have a specific context in mind!