Physical:
* Spine
* Vertebral column
* Spinal column
* Back
* Dorsal column
Figurative:
* Strength: fortitude, courage, determination, grit, resilience, mettle, spirit
* Integrity: honesty, morality, principle, ethics, virtue
* Leadership: authority, command, control, power, dominance
* Support: foundation, base, structure, framework, pillar
Informal:
* Guts
* Nerve
* Spunk
* Willpower
The best synonym will depend on the specific context and the meaning you want to convey. For example, if you're talking about someone's physical spine, then "vertebral column" would be the most accurate synonym. However, if you're talking about someone's inner strength, then "courage" or "grit" might be more appropriate.