* Natural: If you're talking about an artifact as something man-made, then "natural" could be an antonym.
* Original: This could be an antonym if you're talking about an artifact as a copy or replica.
* Authentic: This could be an antonym if you're talking about an artifact as a forgery or imitation.
* Modern: This could be an antonym if you're talking about an artifact as something ancient or from a previous time period.
* Ephemeral: This could be an antonym if you're talking about an artifact as something durable and long-lasting.
For example:
* Artifact (man-made): Antonym: Natural
* Artifact (copy): Antonym: Original
* Artifact (forged): Antonym: Authentic
* Artifact (ancient): Antonym: Modern
* Artifact (permanent): Antonym: Ephemeral
It's important to consider the specific context in which you're using "artifact" to determine the most accurate antonym.