Here are some options, depending on what you want to express:
If "such" means "of this kind" or "similar":
* Different
* Opposite
* Unlike
* Contrary
* Distinct
If "such" means "to this extent" or "so much":
* Not so
* Not that
* Little
* Few
* Minimal
If "such" means "very" or "extremely":
* Not very
* Moderately
* Slightly
* Not at all
It's important to consider the specific context of the sentence to choose the best antonym.
For example:
* "He is such a talented artist." --> "He is not very talented."
* "They have such a big house." --> "They have a small house."
* "The weather is such a disappointment." --> "The weather is delightful."