General abstract nouns related to death:
* Mortality: The state of being subject to death.
* Fatality: A death caused by an accident or disaster.
* Lethality: The quality of being deadly or fatal.
* Death: The end of life.
Abstract nouns related to the consequences of something being fatal:
* Destruction: The act of destroying or being destroyed.
* Ruin: Complete destruction or downfall.
* Loss: The state of no longer having something or someone.
* Extinction: The state of no longer existing.
Abstract nouns emphasizing the potential for something to be fatal:
* Danger: The possibility of harm or injury.
* Risk: The possibility of something bad happening.
* Peril: Serious and immediate danger.
The best choice depends on what you want to emphasize. For example, "The lethality of the virus is a serious concern" focuses on the deadly nature of the virus. However, "The destruction caused by the earthquake was immense" highlights the consequences of the event.