General replacements:
* Replace: This is the most direct and common word.
* Substitute: This implies that something else is being used in place of the original.
* Supplant: This suggests that something is taking over and displacing the original.
* Supersede: This indicates that something is replacing something else that is outdated or no longer relevant.
Specific to people:
* Succeed: This implies taking over a position or role after someone else.
* Inherit: This refers to taking over something, especially a property or title, after someone's death.
* Assume: This means to take on a role or responsibility.
Figurative:
* Fill the void: This implies taking the place of something that is missing.
* Step into someone's shoes: This is a common idiom that means to take over someone's role or responsibilities.
The best word to use will depend on the specific situation and the nuance you want to convey.