Here are a few examples:
Difficult due to spelling:
* Colonel: The "o" sounds like "uh" and the "l" is silent.
* Squirrel: The "ir" makes a unique sound.
* Worcestershire: This one is just plain hard!
Difficult due to unusual sounds:
* Pneumonoultramicroscopicsilicovolcanoconiosis: The longest word in the English language, with many challenging sounds.
* Supercalifragilisticexpialidocious: Another long one, but with a more playful sound.
* Schizophrenia: The "ch" and "ph" combinations can be tricky.
Difficult due to language background:
* Rhythm: This is a common example of a word difficult for English language learners.
* Pronunciation: Ironically, this word can be tricky to pronounce!
Let me know if you have a specific language in mind or if you'd like more examples!