It's often used in biological and medical contexts to describe something that is characterized by variation or irregularity, such as:
* Poikilocytosis: A condition where red blood cells have irregular shapes.
* Poikilothermy: The condition of having a body temperature that varies with the environment (like reptiles).
* Poikiloderma: A skin condition with mottled pigmentation and irregular skin texture.
So, when you see "poikilo" in a word, it generally refers to something that is not uniform or consistent.