General:
* Hands-on: This emphasizes requiring direct physical interaction.
* Manual: This suggests something that needs to be done by hand.
* Hands-occupied: This implies that the hands are busy with something else.
More specific:
* With hands: This is a simple and direct opposite.
* Held: This can be used in the context of holding a device.
* Attached: This might be used for something that needs to be physically held.
Example:
* Hands-free: "The car has a hands-free system for making calls."
* With hands: "You need to hold the phone to use this system, it's not hands-free."
The best antonym will depend on the specific situation and the intended meaning.