Here are some ways to use it:
* "The comedian's acerbic wit had the audience in stitches." (This means the jokes were sharp and biting, but also funny.)
* "The critic's acerbic review of the film was highly unfavorable." (The review was harsh and full of criticism.)
* "Her acerbic remarks stung the group into silence." (Her comments were sharp and cutting, causing discomfort or offense.)
Essentially, something acerbic is like a sharp, sour taste - it's intense and can be unpleasant.