Here's a breakdown:
* "Knickers" is British slang for women's underwear.
* "Twist" implies a state of being twisted or tangled up, symbolizing emotional distress.
Example:
"When she heard the news, she got her knickers in a twist and started shouting at everyone."
Important Note: This idiom is generally considered informal and slightly derogatory and is often used humorously. It's best to avoid using it in formal settings or when talking about someone who is genuinely distressed.