However, you could use "impudence" in a sentence about a scientific discovery if you wanted to express a sense of surprise or audacity:
* "The impudence of the research team to challenge the long-held theory was met with skepticism, but ultimately led to a groundbreaking discovery."
In this example, "impudence" is used to describe the researchers' bold and unexpected move in challenging established ideas.
It's important to note that "impudence" often carries a negative connotation. If you are writing a scientific paper, you might want to choose a more neutral word like "boldness" or "audacity" to describe a similar concept.