* If "hypothesis" is a noun: It should be followed by a period (.) if it's at the end of a sentence.
* Example: "The scientist formulated a new hypothesis."
* If "hypothesis" is part of a longer sentence: It should be followed by a comma (,) if it's followed by more information.
* Example: "The scientist formulated a new hypothesis, which she then tested in the lab."
* If "hypothesis" is part of a list: It should be followed by a colon (:) if it's followed by a list of hypotheses.
* Example: "The scientist proposed several hypotheses: the first, that..."
Ultimately, the correct punctuation depends on the sentence structure and what comes after "hypothesis."