With that correction, the phrase "Antonia y Manuel son" translates to "Antonia and Manuel are..." in English.
You need to complete the sentence with a description of what they are. For example:
* Antonia y Manuel son hermanos. (Antonia and Manuel are siblings.)
* Antonia y Manuel son amigos. (Antonia and Manuel are friends.)
* Antonia y Manuel son médicos. (Antonia and Manuel are doctors.)