Formal:
* Est-ce qu'il (followed by the verb in the infinitive form) - This is the most common and formal way to ask a question in French.
* Example: Est-ce qu'il parle français? (Does he speak French?)
Informal:
* Il (followed by the verb in the appropriate form) - This is more informal, and can be used with friends and family.
* Example: Il mange des fruits? (Does he eat fruit?)
Using "ne" and "pas":
* Ne (followed by the verb in the appropriate form) pas? - This is used to ask if someone *doesn't* do something.
* Example: Ne mange-t-il pas de fruits? (Doesn't he eat fruit?)
Remember: The verb in French is conjugated to match the subject pronoun ("il" for "he").
Choose the most appropriate form based on the context and your level of formality.