Here's the breakdown:
* Standard Italian: "In-spee-ra-re" (with the emphasis on the second syllable "spee")
* English loanword: "In-spīr-āy" (with the emphasis on the first syllable "in")
The English pronunciation is closer to the English word "inspire," while the Italian pronunciation retains the original Italian sound.
It's best to clarify the context when asking about pronunciation. For example, if you're referring to the Italian verb "inspirare," you would use the Italian pronunciation. If you're talking about the English word "inspire" that comes from the Italian word, you would use the English pronunciation.