Here are some ways to say it in English, depending on the context:
Formal:
* Cream (This is the most common English translation)
Informal:
* Cream
* Creme (pronounced with a French accent)
Examples:
* "I like to add a dollop of crème fraîche to my soup." (Formal)
* "Pass me the crème brûlée, please." (Informal)
* "That's a lovely shade of crème." (Informal, referring to a color)