It's a Dothraki phrase meaning "mother of dragons" and is used as a title for Daenerys Targaryen.
Here's a breakdown:
* Shai: Means "mother" in Dothraki
* Ho: Means "dragon" in Dothraki
So, Shai Ho literally translates to "Mother of Dragons".
This phrase is significant because it reflects Daenerys's power and destiny. She becomes a symbol of hope and liberation for many people, embodying the strength and resilience of a true leader.