It's often used in words related to:
* Timekeeping: like "horoscope" (a prediction of future events based on the position of the stars at the time of a person's birth), "horometer" (an instrument for measuring time), and "horology" (the study of timekeeping and the construction of clocks and watches).
* Seasonal Cycles: like "horticulture" (the cultivation of plants), which relates to the seasonal cycles of planting and harvesting.
So, the prefix "horo-" generally refers to time, hours, or seasonal cycles.