General:
* Hum
* Drone
* Thrum
* Rumbling
* Vibration
* Murmur
* Whine
More specific:
* For a mechanical sound: Whirr, rattle, growl, grind
* For a natural sound: Chirp, buzz, chirp, hum, drone, vibrate
* For a ominous sound: Rumble, growl, moan, whine, throb
Figurative:
* For a feeling of unease: Unease, tension, unease, foreboding
* For a feeling of boredom: Monotony, tedium, dullness
The best word depends on the context and the specific sound you want to describe.