Here's a breakdown:
* Tú is the informal "you" used with friends, family, and people you know well.
* Usted is the formal "you" used for everyone else.
* Vos is another informal "you" used in some Spanish-speaking countries, but it's not as widely used as tú.
It's important to note that the use of "Usted" is often regional and depends on the specific context. For example, in some parts of Latin America, it's more common to use "Usted" with everyone, even people you know well.