Formal:
* Mae gen i chwaer. (This is the most literal translation and sounds quite formal)
Informal:
* Mae chwaer gen i. (This is a slightly more informal way of saying it)
* Rwy'n cael chwaer. (This means "I have a sister" but is less common than the other options)
Other options:
* Fy chwaer. (This means "My sister" and could be used in a sentence like "Mae fy chwaer yn byw yn Llundain." - My sister lives in London.)
You can choose the best option based on the situation and your level of formality.