General opposites:
* Separate: This is the most direct opposite, meaning to divide or split into parts.
* Divide: Similar to separate, but can also imply a more deliberate or strategic division.
* Disintegrate: This implies breaking down completely, often into smaller, less cohesive parts.
* Disband: This refers to the dissolution of an organization or group.
Specific to particular contexts:
* Fragment: If you are talking about a physical object, the opposite of amalgamating might be fragmentation.
* Differentiate: If you are talking about concepts or ideas, the opposite might be to differentiate them, or to make them distinct.
* Isolate: If you are talking about people or groups, the opposite might be to isolate them.
To determine the best opposite word, consider the specific situation and what you are trying to convey.