Here's why:
* Nucleolus is a specific structure found within the nucleus of a cell. It's responsible for ribosomal RNA synthesis.
* Antonyms usually represent opposite concepts or features.
Instead of an antonym, consider these related concepts:
* Nucleoplasm: The fluid inside the nucleus that surrounds the nucleolus and chromosomes.
* Chromatin: The complex of DNA and proteins found in the nucleus.
* Cytoplasm: The fluid inside the cell that surrounds the nucleus.
If you're looking for a word to describe something that *lacks* a nucleolus, you might say:
* Anucleolate: This term refers to a cell or organism that does not have a nucleolus.
Ultimately, the best "opposite" depends on the context of your specific usage.