Direct opposites:
* Smile: This expresses pleasure or happiness, the opposite of the pain or discomfort that a wince suggests.
* Grin: Similar to smile, but often indicates a wider, more exaggerated expression.
* Relax: This implies a state of ease and comfort, the opposite of the tense reaction of a wince.
* Enjoy: This suggests taking pleasure in something, the opposite of experiencing something unpleasant.
Other opposites depending on context:
* Welcome: If someone winces at something unpleasant, the opposite could be welcoming something pleasant.
* Embrace: This implies accepting and enjoying something wholeheartedly, the opposite of recoiling from something unpleasant.
* Approve: If someone winces at something they disapprove of, the opposite could be approving of it.
The best opposite for "wince" will depend on the specific situation you're considering.