What is the prefix and suffix to word illuminate?

The word "illuminate" doesn't have a prefix or suffix. It's a base word itself.

However, it comes from the Latin word "illuminare", which is composed of:

* "il-" which is a prefix meaning "in" or "into"

* "luminare" which is a verb meaning "to shine" or "to light"

So, while "illuminate" itself doesn't have a prefix or suffix, it's derived from a Latin word with a prefix.