General:
* Influence (itself can be used as a noun to describe widespread influence)
* Impact
* Reach
* Prevalence
* Dominance
* Hegemony
* Preeminence
* Ubiquity (for something being widespread and common)
More specific:
* Cultural impact
* Global influence
* Political sway
* Social dominance
* Economic power
Figurative:
* Ripple effect
* Seismic shift
The best word will depend on the context and the specific type of influence you are describing.