However, here are some possibilities:
* "Two-fifty" is the most straightforward and likely understood option.
* "Two-fiddy" is a slightly more informal variation.
* "A couple of hundred and a half" is a more descriptive way to say it.
It's also possible that you might hear more specific slang depending on the context, like "a score and a half" (referencing £20 being a "score") or something related to the item being purchased.
Ultimately, the best way to understand London slang for £250 is to listen to how people use it in conversation.