If you mean "written by hand":
* Typeset: This refers to text that has been prepared for printing using a typesetting machine.
* Printed: This is the most straightforward antonym, as it refers to text that has been reproduced using a printing press.
* Digital: This can refer to text that is stored and displayed electronically.
If you mean "unpolished version":
* Published: This refers to a work that has been officially released for public consumption.
* Final draft: This refers to a completed and finalized version of a work.
* Published version: This specifically refers to the version of a work that has been printed and distributed.
If you mean "original copy":
* Copy: This could refer to any reproduction of a manuscript, whether it's a printed copy or a digital version.
* Edition: This can refer to a specific version of a manuscript, especially if there have been multiple revisions or editions.
Ultimately, the best antonym for "manuscript" depends on the specific meaning you want to convey.