General:
* Miscommunication
* Silence
* Gap
* Disconnection
* Breakdown
* Distance
* Isolation
More specific:
* Misunderstanding
* Inability to connect
* Lack of understanding
* Inability to articulate
* Communication breakdown
* Missed connections
* Unclear expectations
Figurative:
* Closed off
* Walls
* Barrier
* Gulf
* Divide
The best word to use will depend on the specific situation and the nuance you want to convey.