1. English: 278 million (82.1%)
2. Spanish: 41.5 million (12.5%)
3. Chinese: 3.5 million (1.1%)
4. Tagalog: 1.6 million (0.5%)
5. Vietnamese: 1.5 million (0.4%)
It's important to note that this list reflects only the most common languages spoken at home, and does not include people who speak other languages but may not use them at home.