* Cities with the most Spanish speakers as a proportion of the population? This would be different than cities with the absolute highest number of speakers.
* Cities where Spanish is the primary language? This excludes places like Miami, where English is the official language, but Spanish is widely spoken.
* Cities that are primarily located in Spanish-speaking countries? This would exclude places like New York City, where Spanish is spoken by a significant portion of the population, but is not the dominant language.
Here are some lists based on different criteria:
By absolute number of Spanish speakers:
* Mexico City, Mexico: With over 20 million inhabitants, a large portion of the population is Spanish-speaking.
* Buenos Aires, Argentina: A major urban center with a population of over 13 million.
* Madrid, Spain: The capital of Spain has a population of over 3.2 million.
* New York City, USA: While not a Spanish-speaking country, NYC has a large Hispanic population, making it a major center for Spanish speakers.
* Santiago, Chile: The capital of Chile boasts a population of over 6.6 million.
By percentage of Spanish speakers:
* Madrid, Spain: Over 99% of the population speaks Spanish.
* Santiago, Chile: Over 99% of the population speaks Spanish.
* Buenos Aires, Argentina: Over 99% of the population speaks Spanish.
* Mexico City, Mexico: Over 99% of the population speaks Spanish.
* Guadalajara, Mexico: Over 99% of the population speaks Spanish.
To get a more precise answer, you need to define your criteria more clearly. Do you want a list of cities with the highest absolute number of Spanish speakers? Or are you looking for cities with the highest percentage of Spanish speakers? Let me know and I can provide a more accurate list.