General:
* The culture region of the Mediterranean is known for its warm climate, ancient history, and delicious cuisine.
* Anthropologists study how culture regions develop and interact with each other.
* The culture region of the American South has a unique history, music, and food traditions.
More specific:
* The culture region of the Great Plains is characterized by its wide-open spaces, indigenous cultures, and cattle ranching.
* The culture region of East Asia is home to a diverse array of languages, religions, and art forms.
* The culture region of the Amazon rainforest is threatened by deforestation and climate change.
Figurative:
* His interests formed a culture region of their own, encompassing literature, music, and philosophy.
* The city's vibrant street art scene represents a distinct culture region within the larger urban landscape.
These are just a few examples, and the best way to use "culture region" depends on the specific context of your sentence.