What does the abbreviation RE mean with reference to a school district?

RE in the context of a school district likely stands for Religious Education.

This would indicate a program or department within the district that focuses on teaching religious concepts, values, and practices.

However, without more context, it's difficult to be sure. It could also be a local abbreviation specific to that school district.

To be certain, you should consult the school district's website or contact them directly.