If you are female and your brother is male:
* Io e mio fratello: This is the most common and formal way to say it.
* Me e mio fratello: This is a more informal way to say it, and it's often used in spoken Italian.
If you are male and your brother is male:
* Io e mio fratello: This is the most common and formal way to say it.
* Me e mio fratello: This is a more informal way to say it, and it's often used in spoken Italian.
If you are female and your brother is female:
* Io e mia sorella: This is the most common and formal way to say it.
* Me e mia sorella: This is a more informal way to say it, and it's often used in spoken Italian.
If you are male and your brother is female:
* Io e mia sorella: This is the most common and formal way to say it.
* Me e mia sorella: This is a more informal way to say it, and it's often used in spoken Italian.
Important Note: The word order is important in Italian. You should always put "io" (I) first and then the name of your brother/sister.